In patients w/ acquired deficiency of vit K-dependent coagulation factors, only use when rapid correction of the prothrombin complex levels is necessary. Patients receiving a vit K antagonist may have an underlying hypercoaguable state. Stop immediately if allergic or anaphylactic-type reactions occur. Risk of thrombosis or disseminated intravascular coagulation. Close monitoring to patients w/ a history of coronary heart disease or MI, liver disease, per- or post-op, neonates, patients at risk of thromboembolic phenomena or disseminated intravascular coagulation or simultaneous inhibitor deficiency. Development of heparin-induced thrombocytopenia, type II. Nephrotic syndrome. Patients on a controlled Na diet. Possibility of passing on infection cannot be totally excluded. Pregnancy & lactation. Childn & adolescent.
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